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\u3000\u3000\u5728\u8f85\u52a9\u751f\u6b96\u6280\u672f\u98de\u901f\u53d1\u5c55\u7684\u4eca\u5929\uff0c\u54c8\u8428\u514b\u65af\u5766\u51ed\u501f\u5176\u5148\u8fdb\u7684\u8bd5\u7ba1\u5a74\u513f\u6280\u672f\u548c\u4e25\u683c\u7684\u533b\u7597\u89c4\u8303\uff0c\u6210\u4e3a\u5168\u7403\u9ad8\u9f84\u53ca\u7279\u6b8a\u9700\u6c42\u5bb6\u5ead\u7684\u91cd\u8981\u9009\u62e9\u3002\u5176\u4e2d\uff0c\u65e0\u521bDNA\u68c0\u6d4b\u6280\u672f\u4f5c\u4e3a\u80da\u80ce\u690d\u5165\u524d\u7b5b\u67e5(PGT)\u4e0e\u5b55\u671f\u4ea7\u68c0\u7684\u5173\u952e\u73af\u8282\uff0c\u5176\u7cbe\u51c6\u6027\u548c\u5b89\u5168\u6027\u76f4\u63a5\u5f71\u54cd\u7740\u598a\u5a20\u7ed3\u5c40\u3002\u672c\u6587\u5c06\u7ed3\u5408\u54c8\u8428\u514b\u65af\u5766<\/a>\u4e34\u5e8a\u5b9e\u8df5\uff0c\u89e3\u6790\u65e0\u521bDNA\u68c0\u6d4b\u5728\u8bd5\u7ba1\u5a74\u513f\u5168\u5468\u671f\u4e2d\u7684\u65e9\u7b5b\u3001\u4e2d\u7b5b\u53ca\u7f8a\u6c34\u7a7f\u523a\u7684\u9002\u7528\u573a\u666f\uff0c\u4e3a\u6c42\u5b50\u5bb6\u5ead\u63d0\u4f9b\u79d1\u5b66\u51b3\u7b56\u4f9d\u636e\u3002<\/p>\n\n\n

\n
\"\"<\/a><\/figure>\n<\/div>\n\n\n

\u3000\u3000\u4e00\u3001\u65e9\u7b5b\u9636\u6bb5\uff1aNICS\u65e0\u521b\u80da\u80ce\u690d\u5165\u6f5c\u80fd\u7b5b\u67e5\u2014\u2014\u7a81\u7834\u4f20\u7edf\u6d3b\u68c0\u7684\u201c\u96f6\u635f\u4f24\u201d\u9769\u547d<\/p>\n\n\n\n

\u3000\u3000\u5728\u8bd5\u7ba1\u5a74\u513f\u5468\u671f\u4e2d\uff0c\u80da\u80ce\u690d\u5165\u524d\u7684\u9057\u4f20\u5b66\u7b5b\u67e5\u662f\u51b3\u5b9a\u6210\u529f\u7387\u7684\u6838\u5fc3\u73af\u8282\u3002\u54c8\u8428\u514b\u65af\u5766\u7387\u5148\u5f15\u5165\u7684NICS(Non-Invasive Chromosome Screening)\u6280\u672f\uff0c\u901a\u8fc7\u5206\u6790\u56ca\u80da\u57f9\u517b\u6db2\u4e2d\u7684\u6e38\u79bbDNA\uff0c\u5b9e\u73b0\u4e86\u5bf9\u80da\u80ce\u67d3\u8272\u4f53\u975e\u6574\u500d\u4f53\u7684\u65e0\u521b\u68c0\u6d4b\u3002\u5176\u6280\u672f\u4f18\u52bf\u4f53\u73b0\u5728\uff1a<\/p>\n\n\n\n

\u3000\u30001.\u8d85\u9ad8\u51c6\u786e\u7387\uff1a\u91c7\u7528\u5355\u7ec6\u80de\u5168\u57fa\u56e0\u7ec4\u6269\u589e\u4e0e\u9ad8\u901a\u91cf\u6d4b\u5e8f\uff0c\u7ed3\u5408AI\u7b97\u6cd5\u5206\u6790\uff0c\u68c0\u6d4b\u51c6\u786e\u7387\u8fbe99%\u4ee5\u4e0a\uff0c\u9634\u6027\u9884\u6d4b\u503c(\u6392\u9664\u67d3\u8272\u4f53\u5f02\u5e38)\u9ad8\u8fbe97%\uff0c\u663e\u8457\u964d\u4f4e\u8bef\u8bca\u98ce\u9669\u3002<\/p>\n\n\n\n

\u3000\u30002.\u96f6\u80da\u80ce\u635f\u4f24\uff1a\u4f20\u7edfPGT-A\u9700\u5bf9\u80da\u80ce\u8fdb\u884c\u6d3b\u68c0\uff0c\u53ef\u80fd\u5f15\u53d11%-3%\u7684\u80da\u80ce\u635f\u4f24\uff0c\u800cNICS\u6280\u672f\u4ec5\u9700\u63d0\u53d65\u03bcL\u57f9\u517b\u6db2\uff0c\u5b8c\u5168\u907f\u514d\u7269\u7406\u6027\u521b\u4f24\u3002<\/p>\n\n\n\n

\u3000\u30003.\u9002\u7528\u4eba\u7fa4\u5e7f\u6cdb\uff1a\u5c24\u5176\u9002\u5408\u5375\u5de2\u529f\u80fd\u65e9\u8870<\/a>(AMH<0.5ng\/ml)\u3001\u53cd\u590d\u79fb\u690d\u5931\u8d25(\u22653\u6b21)\u6216\u9ad8\u9f84(\u226538\u5c81)\u60a3\u8005\u3002\u4f8b\u5982\uff0c\u4e00\u4f4d42\u5c81POF\u60a3\u8005\u5728\u54c8\u8428\u514b\u65af\u5766\u901a\u8fc7NICS\u7b5b\u67e5\uff0c\u4ece5\u679a\u80da\u80ce\u4e2d\u7cbe\u51c6\u7b5b\u9009\u51fa2\u679a\u6574\u500d\u4f53\u80da\u80ce\uff0c\u6700\u7ec8\u6210\u529f\u598a\u5a20\u5e76\u8bde\u4e0b\u5065\u5eb7\u5a74\u513f\u3002<\/p>\n\n\n\n

\u3000\u3000\u4e34\u5e8a\u610f\u4e49\uff1aNICS\u6280\u672f\u5c06\u54c8\u8428\u514b\u65af\u5766\u8bd5\u7ba1\u5a74\u513f\u6574\u4f53\u6210\u529f\u7387\u63d0\u5347\u81f360%-75%\uff0c\u540c\u65f6\u7f29\u77ed\u6cbb\u7597\u5468\u671f\u81f328\u5929\uff0c\u6210\u4e3a\u9ad8\u9f84\u53ca\u590d\u6742\u75c5\u4f8b\u7684\u9996\u9009\u65b9\u6848\u3002<\/p>\n\n\n

\n
\"\"<\/a><\/figure>\n<\/div>\n\n\n

\u3000\u3000\u4e8c\u3001\u4e2d\u7b5b\u9636\u6bb5\uff1a\u5b55\u671f\u65e0\u521bDNA\u68c0\u6d4b\u2014\u2014\u53cc\u80ce\u598a\u5a20\u7684\u201c\u7cbe\u51c6\u907f\u9669\u201d\u7b56\u7565<\/p>\n\n\n\n

\u3000\u3000\u5bf9\u4e8e\u901a\u8fc7\u8bd5\u7ba1\u5a74\u513f\u6280\u672f\u6210\u529f\u598a\u5a20\u7684\u5973\u6027\uff0c\u5b55\u4e2d\u671f(12-26\u5468)\u7684\u65e0\u521bDNA\u68c0\u6d4b\u662f\u8bc4\u4f30\u80ce\u513f\u67d3\u8272\u4f53\u5f02\u5e38\u98ce\u9669\u7684\u5173\u952e\u6b65\u9aa4\u3002\u7136\u800c\uff0c\u54c8\u8428\u514b\u65af\u5766\u751f\u6b96\u533b\u5b66\u4e2d\u5fc3<\/a>\u660e\u786e\u6307\u51fa\uff1a\u53cc\u80ce\u6216\u591a\u80ce\u598a\u5a20\u9700\u8c28\u614e\u9009\u62e9\u65e0\u521b\u68c0\u6d4b\uff0c\u539f\u56e0\u5982\u4e0b\uff1a<\/p>\n\n\n\n

\u3000\u30001.\u68c0\u6d4b\u5e72\u6270\u98ce\u9669\uff1a\u53cc\u80ce\u598a\u5a20\u65f6\uff0c\u6bcd\u4f53\u8840\u6d46\u4e2d\u6e38\u79bb\u80ce\u513fDNA(cffDNA)\u6765\u6e90\u590d\u6742\uff0c\u82e5\u4e00\u80ce\u6b63\u5e38\u3001\u53e6\u4e00\u80ce\u5f02\u5e38\uff0c\u65e0\u521b\u68c0\u6d4b\u53ef\u80fd\u56e0\u4fe1\u53f7\u6df7\u5408\u800c\u663e\u793a\u201c\u4f4e\u98ce\u9669\u201d\uff0c\u5bfc\u81f4\u6f0f\u8bca\u3002<\/p>\n\n\n\n

\u3000\u30002.\u5047\u9633\u6027\u7387\u4e0a\u5347\uff1a\u7814\u7a76\u663e\u793a\uff0c\u53cc\u80ce\u65e0\u521b\u68c0\u6d4b\u7684\u5047\u9633\u6027\u7387(5%-10%)\u663e\u8457\u9ad8\u4e8e\u5355\u80ce(0.5%)\uff0c\u53ef\u80fd\u5f15\u53d1\u4e0d\u5fc5\u8981\u7684\u7f8a\u6c34\u7a7f\u523a\u3002<\/p>\n\n\n\n

\u3000\u30003.\u54c8\u8428\u514b\u65af\u5766\u4e34\u5e8a\u89c4\u8303\uff1a\u5bf9\u4e8e\u53cc\u80ce\u8bd5\u7ba1\u598a\u5a20\uff0c\u533b\u751f\u901a\u5e38\u5efa\u8bae\u76f4\u63a5\u9009\u62e9\u7f8a\u6c34\u7a7f\u523a(18-22\u5468)\u8fdb\u884c\u786e\u8bca\uff0c\u5176\u51c6\u786e\u7387\u63a5\u8fd1100%\uff0c\u4e14\u53ef\u540c\u65f6\u68c0\u6d4b\u5fae\u7f3a\u5931\u7efc\u5408\u5f81\u7b49\u65e0\u521b\u68c0\u6d4b\u65e0\u6cd5\u8986\u76d6\u7684\u75be\u75c5\u3002<\/p>\n\n\n\n

\u3000\u3000\u6848\u4f8b\u53c2\u8003\uff1a\u4e00\u4f4d39\u5c81\u8bd5\u7ba1\u53cc\u80ce\u5b55\u5987\u5728\u54c8\u8428\u514b\u65af\u5766\u67d0\u4e2d\u5fc3\u63a5\u53d7\u65e0\u521b\u68c0\u6d4b\uff0c\u7ed3\u679c\u663e\u793a\u201c21\u4e09\u4f53\u9ad8\u98ce\u9669\u201d\uff0c\u4f46\u540e\u7eed\u7f8a\u6c34\u7a7f\u523a\u8bc1\u5b9e\u4e24\u80ce\u513f\u5747\u6b63\u5e38\u3002\u6b64\u6848\u4f8b\u51f8\u663e\u4e86\u53cc\u80ce\u598a\u5a20\u4e2d\u65e0\u521b\u68c0\u6d4b\u7684\u5c40\u9650\u6027\u3002<\/p>\n\n\n\n

\u3000\u3000\u4e09\u3001\u7ec8\u6781\u8bca\u65ad\uff1a\u7f8a\u6c34\u7a7f\u523a\u2014\u2014\u9057\u4f20\u75c5\u7b5b\u67e5\u7684\u201c\u91d1\u6807\u51c6\u201d<\/p>\n\n\n\n

\u3000\u3000\u5c3d\u7ba1\u65e0\u521bDNA\u68c0\u6d4b\u5177\u6709\u65e0\u521b\u3001\u5feb\u6377\u7684\u4f18\u52bf\uff0c\u4f46\u7f8a\u6c34\u7a7f\u523a\u4ecd\u662f\u786e\u8bca\u67d3\u8272\u4f53<\/a>\u5f02\u5e38\u548c\u5355\u57fa\u56e0\u9057\u4f20\u75c5\u7684\u7ec8\u6781\u624b\u6bb5\u3002\u54c8\u8428\u514b\u65af\u5766\u751f\u6b96\u533b\u5b66\u4e2d\u5fc3\u5728\u4ee5\u4e0b\u573a\u666f\u4e2d\u5f3a\u5236\u8981\u6c42\u7f8a\u6c34\u7a7f\u523a\uff1a<\/p>\n\n\n\n

\u3000\u30001.\u9ad8\u98ce\u9669\u4eba\u7fa4\uff1a\u5982\u592b\u5987\u4e00\u65b9\u643a\u5e26\u5730\u4e2d\u6d77\u8d2b\u8840\u3001\u810a\u9ad3\u6027\u808c\u840e\u7f29\u75c7(SMA)\u7b49\u5355\u57fa\u56e0\u75c5\uff0c\u6216\u65e0\u521b\u68c0\u6d4b\u63d0\u793a\u9ad8\u98ce\u9669\u3002<\/p>\n\n\n\n

\u3000\u30002.\u7ed3\u6784\u5f02\u5e38\u8d85\u58f0\u63d0\u793a\uff1a\u82e5\u5b55\u4e2d\u671fB\u8d85\u53d1\u73b0\u80ce\u513f\u5fc3\u810f\u5f3a\u5149\u70b9\u3001\u80be\u76c2\u5206\u79bb\u7b49\u8f6f\u6307\u6807\uff0c\u9700\u901a\u8fc7\u7f8a\u6c34\u7a7f\u523a\u6392\u9664\u67d3\u8272\u4f53\u5fae\u7f3a\u5931\u3002<\/p>\n\n\n\n

\u3000\u30003.\u591a\u80ce\u598a\u5a20\u786e\u8bca\u9700\u6c42\uff1a\u5bf9\u4e8e\u53cc\u80ce\u4e2d\u4e00\u80ce\u5f02\u5e38\u7684\u60c5\u51b5\uff0c\u7f8a\u6c34\u7a7f\u523a\u53ef\u7cbe\u51c6\u5b9a\u4f4d\u95ee\u9898\u80ce\u513f\uff0c\u4e3a\u4ea7\u524d\u5e72\u9884\u63d0\u4f9b\u4f9d\u636e\u3002<\/p>\n\n\n\n

\u3000\u3000\u6280\u672f\u4fdd\u969c\uff1a\u54c8\u8428\u514b\u65af\u5766\u91c7\u7528\u8d85\u58f0\u5f15\u5bfc\u4e0b\u7684\u7ec6\u9488\u7a7f\u523a\u6280\u672f\uff0c\u914d\u5408\u5feb\u901f\u67d3\u8272\u4f53\u5206\u6790(FISH)\uff0c\u5c06\u7f8a\u6c34\u7a7f\u523a\u7684\u6d41\u4ea7\u98ce\u9669\u63a7\u5236\u57280.1%\u4ee5\u4e0b\uff0c\u8fdc\u4f4e\u4e8e\u56fd\u9645\u5e73\u5747\u6c34\u5e73(0.5%)\u3002<\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

\u3000\u3000\u56db\u3001\u54c8\u8428\u514b\u65af\u5766\u7684\u6280\u672f\u4f18\u52bf\uff1a\u5168\u5468\u671f\u7cbe\u51c6\u7ba1\u7406<\/p>\n\n\n\n

\u3000\u3000\u54c8\u8428\u514b\u65af\u5766\u8bd5\u7ba1\u5a74\u513f\u6280\u672f\u7684\u6838\u5fc3\u7ade\u4e89\u529b\uff0c\u5728\u4e8e\u5c06\u65e0\u521b\u68c0\u6d4b\u4e0e\u4e2a\u6027\u5316\u8bca\u7597\u6df1\u5ea6\u878d\u5408\uff1a<\/p>\n\n\n\n

\u3000\u30001.\u65e9\u7b5b-\u4e2d\u7b5b-\u4ea7\u7b5b\u65e0\u7f1d\u8854\u63a5\uff1a\u4eceNICS\u80da\u80ce\u7b5b\u67e5\u5230\u5b55\u671f\u65e0\u521b\/\u7f8a\u6c34\u7a7f\u523a\uff0c\u5f62\u6210\u95ed\u73af\u5f0f\u9057\u4f20\u75c5\u9632\u63a7\u4f53\u7cfb\u3002<\/p>\n\n\n\n

\u3000\u30002.\u591a\u5b66\u79d1\u56e2\u961f\u534f\u4f5c\uff1a\u751f\u6b96\u533b\u5b66\u4e13\u5bb6\u3001\u9057\u4f20\u54a8\u8be2\u5e08\u4e0e\u4ea7\u79d1\u533b\u751f\u5171\u540c\u5236\u5b9a\u65b9\u6848\uff0c\u4f8b\u5982\u4e3aRH\u9634\u6027\u8840\u578b\u5b55\u5987\u63d0\u524d\u51c6\u5907\u6297D\u514d\u75ab\u7403\u86cb\u767d\uff0c\u964d\u4f4e\u6eb6\u8840\u98ce\u9669\u3002<\/p>\n\n\n\n

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